Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies.
Salvatore BenvengaSilvia Martina FerrariGiusy EliaFrancesca RagusaArmando PatrizioSabrina Rosaria PaparoStefania CamastraDaniela BonofiglioAlessandro AntonelliPoupak FallahiPublished in: Nutrients (2020)
Nutraceuticals are defined as a food, or parts of a food, that provide medical or health benefits, including the prevention of different pathological conditions, and thyroid diseases, or the treatment of them. Nutraceuticals have a place in complementary medicines, being positioned in an area among food, food supplements, and pharmaceuticals. The market of certain nutraceuticals such as thyroid supplements has been growing in the last years. In addition, iodine is a fundamental micronutrient for thyroid function, but also other dietary components can have a key role in clinical thyroidology. Here, we have summarized the in vitro, and in vivo animal studies present in literature, focusing on the commonest nutraceuticals generally encountered in the clinical practice (such as carnitine, flavonoids, melatonin, omega-3, resveratrol, selenium, vitamins, zinc, and inositol), highlighting conflicting results. These experimental studies are expected to improve clinicians' knowledge about the main supplements being used, in order to clarify the potential risks or side effects and support patients in their use.
Keyphrases
- human health
- healthcare
- risk assessment
- clinical practice
- end stage renal disease
- case control
- newly diagnosed
- ejection fraction
- public health
- systematic review
- chronic kidney disease
- climate change
- magnetic resonance imaging
- palliative care
- computed tomography
- magnetic resonance
- health insurance
- patient reported outcomes
- replacement therapy