Phenotypic variability in LAMA3-associated amelogenesis imperfecta.

Shih-Kai WangHong ZhangYin-Lin WangFigen SeymenMine KoruyucuJames P SimmerJan C-C Hu

Published in: Oral diseases (2022)

Heterozygous LAMA3 mutations can cause generalized enamel defects (AI1A) with variable expressivity. Laminin-332 is critical not only for appositional growth but also enamel maturation.

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