Montelukast potentiates the antiinflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage.
Sherien A AbdelhadyMennatallah A AliTamer A Al-ShafieEbtsam M AbdelmawgoudDalia M YacoutMahmoud M El-MasPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2021)
While montelukast equally enhances antiinflammatory action of diclofenac or celecoxib via downregulating iNOS/COX2/LTs/IL-6 signaling, its gastroprotective action is preferentially potentiated by celecoxib.