Direct Oral Anticoagulants Versus Warfarin for Treatment of Thrombosis or Atrial Fibrillation in Patients With Cirrhosis: A Retrospective Cohort Study.
Eric M CoonsBritta A StaubesAshley L CaseyStephanie A Elagizi-YoussefAlaa E MohammedNikhil SharmaElle R KlinePublished in: The Annals of pharmacotherapy (2021)
Treatment with DOACs in patients with cirrhosis was associated with a similar rate of major bleeding compared with warfarin. Inclusion of CTP class C patients in future studies remains valuable to evaluate safety and efficacy of DOACs in this population.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- venous thromboembolism
- oral anticoagulants
- left atrial
- catheter ablation
- end stage renal disease
- left atrial appendage
- heart failure
- chronic kidney disease
- ejection fraction
- pulmonary embolism
- newly diagnosed
- percutaneous coronary intervention
- coronary artery disease
- peritoneal dialysis
- prognostic factors
- replacement therapy