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Characterization and population dynamics of germ cells in adult macaque testicular cultures.

Swati SharmaStefan SchlattAns Van PeltNina Neuhaus
Published in: PloS one (2019)
Our findings demonstrate maintenance of macaque germ cell subpopulations in vitro. This study provides novel perspective and proof that macaques could be used as a research model for establishing in vitro germ cell-somatic cell cultures, to identify ideal culture conditions for long-term maintenance of primate germ cell subpopulation in vitro.
Keyphrases
  • germ cell
  • induced apoptosis
  • single cell
  • cell cycle arrest
  • copy number
  • oxidative stress
  • gene expression