Causal relationship between affect disorders and endometrial cancer: a Mendelian randomisation study.

Yewu SunShuo GengChunmeng FuXiaoyan SongHua LinYidan Xu

Published in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2024)

Major depressive disorder(MDD), anxiety and stress-related disorders(ASRD) are not genetically responsible for endometrial cancer. We consider that emotional disorders may affect endometrial cancer indirectly by affecting body mass index. This study provides us with new insights to better understand the aetiology of endometrial cancer and inform prevention strategies.

Keyphrases

weight loss
endometrial cancer
major depressive disorder
body mass index
weight gain
bipolar disorder
sleep quality