An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood.

Ezio BonifacioAndreas WeißChristiane WinklerMarkus HippichMarian J RewersJorma ToppariÅke LernmarkJin-Xiong SheWilliam A HagopianJeffrey P KrischerKendra VehikDesmond A SchatzBeena AkolkarAnette-Gabriele Zieglernull null

Published in: Diabetes care (2021)

The risk of developing islet autoimmunity declines exponentially with age, and the influence of major genetic factors on this risk is limited to the first few years of life.

Keyphrases

genome wide
early life
copy number
childhood cancer
dna methylation