Effect of sirolimus on muscle in inclusion body myositis observed with magnetic resonance imaging and spectroscopy.

Harmen ReyngoudtPierre-Yves BaudinEricky Caldas de Almeida AraújoDamien BachassonJean-Marc BoisserieKubéraka MariampillaiMélanie AnnoussamyYves AllenbachJean-Yves HogrelPierre G CarlierBenjamin MartyOlivier Benveniste

Published in: Journal of cachexia, sarcopenia and muscle (2024)

P MRS can discern measurable differences between placebo and sirolimus-treated IBM patients, offering promise for future therapeutic trials in idiopathic inflammatory myopathies such as IBM.

Keyphrases

magnetic resonance imaging
newly diagnosed
end stage renal disease
ejection fraction
prognostic factors
skeletal muscle
high resolution
computed tomography
magnetic resonance
interstitial lung disease
big data
patient reported outcomes
contrast enhanced
systemic sclerosis
idiopathic pulmonary fibrosis
open label