Concurrent POLE hotspot mutations and mismatch repair deficiency/microsatellite instability in endometrial cancer: A challenge in molecular classification.

Sara MoufarrijAndrea GazzoSatshil RanaPier SelenicaNadeem R Abu-RustumLora H EllensonYing L LiuBritta WeigeltAmir Momeni-Boroujeni

Published in: Gynecologic oncology (2024)

POLEmut/MMRd ECs may be genetically distinct. Further studies are needed to assess the impact on outcomes and treatment response within this population.

Keyphrases

endometrial cancer
machine learning
deep learning
locally advanced
case control
replacement therapy
type diabetes
genetic diversity