Assessment of Plasma Sodium to Potassium Ratio, Renal Function, Markers of Oxidative Stress, Inflammation, and Endothelial Dysfunction in Nigerian Hypertensive Patients.
Oloruntoba Ayodele EkunFolasade DanielPhilip AdebolaAdeola Olubunmi AjibareOyeronke O EkunOluwafunso O OmogoroyeOluwafemi S IloriBankole J OluwasayoMary F OshundunSade R OyegbamiPublished in: International journal of hypertension (2020)
An increase in Na+/K+, urea, hs-CRP, ferritin, MDA, and BMI and a decrease in eGFR, glutathione, and superoxide dismutase were associated with an increased risk of hypertension complication. Abnormal values of markers of oxidative stress, inflammation, and endothelial function could impact deleterious effects on the cardiovascular system among hypertensive Nigerians. A decreased bicarbonate possibly suggests an occult acid-base imbalance among hypertensive volunteers.