LPS-mediated release of ATP from urothelial cells occurs by lysosomal exocytosis.

Andrew SilberfeldBrittany ChavezChinonso ObidikeStephanie DaughertyWilliam C de GroatJonathan M Beckel

Published in: Neurourology and urodynamics (2020)

These data indicate that LPS-induced ATP release from urothelial cells is mediated by lysosomal exocytosis, a vesicular mechanism distinctly separate from non-vesicular release via pannexin channels.

Keyphrases

induced apoptosis
lps induced
inflammatory response
cell cycle arrest
high grade
endoplasmic reticulum stress
signaling pathway
oxidative stress
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cell proliferation
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