Familial motor neuron disease: co-occurrence of PLS and ALS (-FTD).
Eva M J de BoerKoen C DemaegdCharlotte I de BieJan Herman VeldinkLeonard H Van Den BergMichael A Van EsPublished in: Amyotrophic lateral sclerosis & frontotemporal degeneration (2023)
The consistent observation of PLS patients with a positive family history for MND, evident in both our study and the literature, implies the presence of shared underlying genetic factors between PLS and ALS. However, these factors are yet to be elucidated.