Area under the curve achievement of once daily tobramycin in children with cystic fibrosis during clinical care.
Jake M BrockmeyerRussell T WiseElizabeth B BurgenerCarlos E MillaAdam FrymoyerPublished in: Pediatric pulmonology (2020)
Achievement of a narrow AUC24 target is challenging during clinical care, and dose individualization is needed in most children with CF. Implementing a BF approach for estimating AUC24 in children with CF is supported.