Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop.

Tingting XuMengyan XieXinming JingHuning JiangXi WuXinzhu WangYongqian Shu

Published in: Journal of translational medicine (2023)

The newly identified miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop plays an important role in inflammation-related GC progression and may serve as a promising therapeutic target for GC.

Keyphrases

cell cycle
cell proliferation
transcription factor
oxidative stress
gas chromatography
mass spectrometry