Exosomal transfer of miR-181b-5p confers senescence-mediated doxorubicin resistance via modulating BCLAF1 in breast cancer.

Shaorong ZhaoTeng PanJinhai DengLixia CaoJose M VicencioJingjing LiuGuanglin ZhouTony T Ng Jin Zhang

Published in: British journal of cancer (2022)

Our data suggests exo-miR-181b-5p as a prognostic biomarker and a therapeutic potential for exo-miR-181b-5p inhibitors in the treatment of doxorubicin-resistant BC patients.

Keyphrases

end stage renal disease
drug delivery
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
cancer therapy
prognostic factors
dna damage
endothelial cells
signaling pathway
big data
machine learning
oxidative stress