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Spatially Informed Gene Signatures for Response to Immunotherapy in Melanoma.

Thazin Nwe AungJonathan WarrellSandra Martinez-MorillaNiki GavrielatouIoannis A VathiotisVesal YaghoobiHarriet M KlugerMark B GersteinDavid L Rimm
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
We conclude that the spatially defined compartment signatures utilize tumor and tumor microenvironment-specific information, leading to more accurate prediction of treatment outcome, and thus merit prospective clinical assessment.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • genome wide identification
  • healthcare
  • mass spectrometry
  • social media
  • genome wide analysis