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Implementing MyChoice® CDx HRD testing for the Nordics: lessons from 2021 to 2023.

Lea Milling KorsholmVerena BroeckerMansoor Raza MirzaMaria Rossing
Published in: Acta oncologica (Stockholm, Sweden) (2024)
The myChoice® CDx Nordic core facility has been well received among the Nordic countries and provides new insights on the influence of national guidelines on HRD testing. Overall, we experienced an efficient turnaround time and a high fraction of conclusive results. Interestingly, prior somatic BRCA testing is redundant when assessing HRD status through myChoice® CDx test since somatic BRCA screening is already a significant component of the myChoice® CDx test. Thus, it should be considered to omit prior somatic BRCA testing to ensure a rationalised HRD diagnostic flow optimised for clinical use.
Keyphrases
  • copy number
  • quality improvement
  • clinical practice
  • genome wide