Neurocognitive and behavioral functioning in adolescents with sleep-disordered breathing: a population-based, dual-energy X-ray absorptiometry study.
S S FryeJulio Fernandez-MendozaS L CalhounJ GainesM D SawyerFan HeD LiaoA N VgontzasE O BixlerPublished in: International journal of obesity (2005) (2017)
Central obesity, an etiopathogenic mechanism of OSA, is more strongly associated with neurocognitive and behavioral problems in adolescents than SDB alone. Deficits in low-order (vigilance) and high-order (executive) functions and behavioral problems observed in adolescents with OSA are primarily associated with increased central adiposity, a finding not entirely captured with less precise measures of obesity. These data support that OSA and its associated neurocognitive and behavioral morbidity are related to underlying metabolic dysfunction as early as adolescence.
Keyphrases
- dual energy
- young adults
- computed tomography
- obstructive sleep apnea
- insulin resistance
- physical activity
- mental health
- metabolic syndrome
- weight gain
- weight loss
- bipolar disorder
- type diabetes
- image quality
- positive airway pressure
- depressive symptoms
- high fat diet induced
- magnetic resonance imaging
- body composition
- electronic health record
- big data
- skeletal muscle
- body mass index
- working memory
- machine learning
- sleep apnea