Portable and Recyclable Luminescent Lanthanide Coordination Polymer Film Sensors for Adenosine Triphosphate in Urine.
Li KaisuYang SonglinShuangyan WuZhang YingLei WangAndrei S PotapovXiaolin YuYa-Guang SunNa SunMingchang ZhuPublished in: ACS applied materials & interfaces (2024)
Adenosine triphosphate (ATP) is a small molecule that is released to the urine from bladder urothelial cells and the bladder mucosal band of the human body. In certain cases, ATP can serve as a biomarker in bladder disease. For the practical applicability of luminescent sensors for ATP in urine, it is significant to find a new strategy for making the detection progress simple and available for in-field urine analysis. Here, a novel luminescent lanthanide coordination polymer (Tb-BPA) was designed and synthesized for quick and sensitive detection of ATP through luminescence quenching with a quenching constant of 4.90 × 10 3 M -1 and a detection limit of 0.55 × 10 -6 M. Besides, Tb-BPA has excellent anti-interference ability and can detect ATP in simulated urine with a small relative standard deviation (<4%). Moreover, the luminescent polyacrylonitrile nanofiber films modified by Tb-BPA were prepared by electrospinning and were used for ATP visual detection. Notably, this film is easy to recover and reuse, and maintains good detection performance after at least 7 cycles.
Keyphrases
- sensitive detection
- loop mediated isothermal amplification
- energy transfer
- quantum dots
- metal organic framework
- small molecule
- spinal cord injury
- mycobacterium tuberculosis
- real time pcr
- label free
- endothelial cells
- induced apoptosis
- urinary tract
- low cost
- single molecule
- endoplasmic reticulum stress
- reduced graphene oxide
- wastewater treatment
- light emitting
- protein protein