Genetic determinants of renal scarring in children with febrile UTI.

Therese RosenbladMagnus LindénInes AmbitePer BrandströmSverker HanssonGabriela Godaly

Published in: Pediatric nephrology (Berlin, Germany) (2024)

In this nationwide study of genetic susceptibility to RS after febrile UTIs in infancy, we identified a profile dominated by mitochondrial polymorphisms. This profile can serve as a predictor of future complications, including RS and recurrent UTIs.

Keyphrases

urinary tract infection
genome wide
copy number
young adults
oxidative stress
chemotherapy induced
risk factors
dna methylation
gene expression
body mass index