Exploratory Study of Associations Between DNA Repair and Oxidative Stress Gene Polymorphisms and Cognitive Problems Reported by Postmenopausal Women With and Without Breast Cancer.

John D MerrimanSusan M SereikaYvette P ConleyTheresa A KoleckYehui ZhuMary L PhillipsMichele A BertocciAdam M BrufskyCatherine M Bender

Published in: Biological research for nursing (2018)

Chemotherapy plus anastrozole, depressive symptoms, and presence of neuropathic symptoms may predict more frequent cognitive problems during systemic therapy that later resolve. Mood dysregulation before therapy may predict persistent cognitive problems during therapy. ERCC5 genotype may influence frequency of cognitive problems after controlling for these risk factors.

Keyphrases

dna repair
mental health
postmenopausal women
depressive symptoms
oxidative stress
dna damage
risk factors
bone mineral density
sleep quality
stem cells
bipolar disorder
squamous cell carcinoma
young adults
cell therapy
body composition
signaling pathway
induced apoptosis
endoplasmic reticulum stress