Serum vitamin D-binding protein (VDBP) concentration and rs7041 genotype may be associated with preterm labor.
Min-Chul ChoIn Ae ChoHyun Kyoung SeoMin Ji KangJae Yoon JoJeong Kyu ShinSoon Ae LeeSeung Chan KimRock Beum KimWon Jun ChoiPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2022)
Pregnant women with the VDBP rs7041(c.1296 T > G) T allele genotype had reduced serum levels of bioavailable 25(OH)D and were more likely to develop PTL. Therefore, if the T allele is found in the VDBP rs7041 SNP genotyping test before or during pregnancy, more careful prenatal care may be required because of the increased risk of PTL.