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A novel rapid immunoassay of serum type IV collagen 7S for the diagnosis of fibrosis stage of nonalcoholic fatty liver diseases.

Toshihide ShimaYukie OhtakakiHitoshi KikuchiHiroki UchinoMitsuo IsomuraKatsumi AoyagiHirohisa OyaTakayuki KatayamaYasuhide MitsumotoMasayuki MizunoAtsushi UmemuraKanji YamaguchiYoshito ItohTakeshi Okanoue
Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2021)
The T4C7S CLEIA correlated well with the T4C7S RIA. Favorably, the T4C7S CLEIA has a higher sensitivity and rapid measurement time and requires a small sample volume; thus, it is a promising and popular biomarker for fibrosis stage diagnosis in NAFLD.
Keyphrases
  • loop mediated isothermal amplification
  • sensitive detection