Human Epidermal Growth Factor Receptor 2-Low Breast Cancer Brain Metastases: An Opportunity for Targeted Systemic Therapies in a High-Need Patient Population.
Rania ChehadeSharon Nofech-MozesAnna PlotkinKevin Yijun FanSunit DasArjun SahgalVeronika MoravanKatarzyna Joanna JerzakPublished in: JCO precision oncology (2024)
Among patients with surgically resected BrM, a high proportion of those with metastatic triple-negative BC and HR+/HER2- disease have HER2-low BrM with potential to benefit from HER2-targeted therapy.
Keyphrases
- epidermal growth factor receptor
- brain metastases
- small cell lung cancer
- tyrosine kinase
- advanced non small cell lung cancer
- endothelial cells
- squamous cell carcinoma
- case report
- lymph node
- cancer therapy
- human health
- induced pluripotent stem cells
- risk assessment
- pluripotent stem cells
- prognostic factors
- drug induced