Opioid-related adverse drug events in surgical patients: risk factors and association with clinical outcomes.
Chin Hang YiuDanijela GnjidicAsad E PatanwalaIan FongDavid BegleyKok Eng KhorJoanne RimingtonBernadette BugejaJonathan PenmPublished in: Expert opinion on drug safety (2022)
Risk factors for general ORADEs were advanced age, specific comorbidities, use of benzodiazepines or gabapentinoids and higher opioid dose. Routine use of opioids with gabapentinoids should be avoided and only used after careful consideration.