Acute coronary syndrome and acute kidney injury: role of inflammation in worsening renal function.

Jorge Ortega-HernándezRashidi SpringallFausto Sánchez-MuñozJulio-C Arana-MartinezHéctor González-PachecoRafael Bojalil

Published in: BMC cardiovascular disorders (2017)

Inflammation and its components play an important role in the worsening of renal function in ACS. IL-10, ET-1, IL-1β, TnI, RvD1 and LxA4 represent mediators that might be associated with ACS-AKI. IL-6, ET-1, NT-ProBNP might represent crossroads for several physiopathological pathways involved in "de novo cardiac injury leading to de novo kidney injury".

Keyphrases

acute coronary syndrome
acute kidney injury
oxidative stress
percutaneous coronary intervention
antiplatelet therapy
cardiac surgery
heart failure
coronary artery disease
atrial fibrillation