Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.
Xavier NadalCarmen Del RíoSalvatore CasanoBelén PalomaresCarlos Ferreiro-VeraCarmen NavarreteCarolina Sánchez-CarnereroIrene CantareroMaria Luz BellidoStefan MeyerGaetano MorelloGiovanni AppendinoEduardo MuñozPublished in: British journal of pharmacology (2017)
Δ9 -THCA shows potent neuroprotective activity, which is worth considering for the treatment of Huntington's disease and possibly other neurodegenerative and neuroinflammatory diseases.