Targeted sequencing of candidate gene regions for myelofibrosis in dogs.

Amelia G Campbell Davis M SeeligJoan D BeckmanKatie M MinorDaniel A HeinrichSteven G FriedenbergJaime F ModianoEva Furrow

Published in: Journal of veterinary internal medicine (2022)

Somatic variants might initiate or perpetuate myelofibrosis in dogs. Our findings suggest the occurrence of clonal hematopoiesis in dogs, with increasing incidence with age, as observed in humans.

Keyphrases

copy number
risk assessment
risk factors
genome wide
gene expression
cancer therapy
dna methylation