Depot-specific characteristics of adipose tissue-derived stromal cells in thyroid-associated orbitopathy.

Janice Siu Chong WongWai Kit ChuBenjamin Fuk-Loi LiChi-Pui PangKelvin Kam-Lung Chong

Published in: The British journal of ophthalmology (2018)

ADSCs from different adipose depots of the same donors exhibited similar mesenchymal phenotypes but differed significantly in adipogenic, myofibrogenic potentials and associated HA synthesis. These depot-specific characteristics of ADSCs may contribute to site-specific adipose tissue involvement in TAO.

Keyphrases

adipose tissue
insulin resistance
high fat diet
stem cells
bone marrow