Presence of SARS-CoV-2 in a Cornea Transplant.

Myriem Otmani IdrissiJean-Pierre BaudoinAnne-Line ChateauSarah AherfiMarielle Bedotto-BuffetAlain LatilHubert LepidiJacques ChiaroniChristophe PicardJean-Louis MegeBernard La Scola Soraya Mezouar

Published in: Pathogens (Basel, Switzerland) (2021)

Although the cornea graft was found to be negative by qRT-PCR, we were able to show the presence of SARS-CoV-2 in corneal cells expressing the SARS-CoV-2 receptor, ACE2. Taken together, our findings may have important implications for the use of corneal tissue in graft indications and open the debate on SARS-CoV-2 transmissibility.

Keyphrases

sars cov
respiratory syndrome coronavirus
induced apoptosis
optical coherence tomography
minimally invasive
wound healing
angiotensin ii
cell proliferation
signaling pathway