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Adaptation of prelimbic cortex mediated by IL-6/STAT3/Acp5 pathway contributes to the comorbidity of neuropathic pain and depression in rats.

Yu-Ting ZhaoJie DengHe-Ming LiuJia-You WeiHai-Ting FanMeng LiuTing XuTing-Feng ChenJing-Yi HeWei-Ming SunTao-Yu JiaXue-Qin ZhangWen-Jun Xin
Published in: Journal of neuroinflammation (2022)
These data suggest that the adaptation of PrL mediated by IL-6/STAT3/Acp5 pathway contributed to the comorbidity of neuropathic pain/depression induced by SNI.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • depressive symptoms
  • cell proliferation
  • sleep quality
  • electronic health record
  • functional connectivity
  • big data
  • physical activity
  • machine learning
  • deep learning