Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN overlap neoplasms.

Emma C DiFilippoGiacomo ColtroRyan M CarrAbhishek A MangaonkarMoritz BinderShakila P KhanVilmarie RodriguezNaseema GangatAlexandra WolanskyjRajiv K PruthiDong ChenRong HeDavid S ViswanathaTerra LashoChristy FinkeAyalew TefferiAnimesh PardananiMirinal S Patnaik

Published in: Leukemia (2020)

Keyphrases

transcription factor
copy number
early onset
dna repair
gene expression
dna methylation