Pancreatic cancer as a sentinel for hereditary cancer predisposition.

Erin L YoungBryony A ThompsonDeborah W NeklasonMatthew A FirpoTheresa WernerRussell BellJustin BergerAlison FraserAmanda GammonCathryn KoptiuchWendy K KohlmannLeigh NeumayerDavid E GoldgarSean J MulvihillLisa A Cannon-AlbrightSean V Tavtigian

Published in: BMC cancer (2018)

With the inclusion of both HBOC and CRC susceptibility genes in a panel test, unselected pancreatic cancer cases act as a useful sentinel cancer to identify asymptomatic at-risk relatives who could benefit from relevant HBOC and CRC surveillance measures.

Keyphrases

papillary thyroid
squamous cell
public health
genome wide
gene expression
childhood cancer
transcription factor