A small circulating miRNAs signature predicts mortality and adverse cardiovascular outcomes in chronic hemodialysis patients.

Davide BolignanoMarta GrecoPierangela PrestaAnila DuniCaterina VitaEthymios PappasMaria MirabelliLampros LakkasKaterina K NakaAntonio BrunettiDaniela Patrizia FotiMichele AndreucciGiuseppe CoppolinoEvangelia Dounousi

Published in: Clinical kidney journal (2023)

Lower circulating levels of miRNA 30-5p, 23a-3p and 451a in HD patients may reflect cardiac abnormalities and predict a higher risk of worse clinical outcomes in the short mid-term. Future studies on larger HD populations are needed to generalize these findings.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
peritoneal dialysis
prognostic factors
risk factors
emergency department
left ventricular
coronary artery disease
adverse drug
patient reported
drug induced