Ischemic stroke alters immune cell niche and chemokine profile in mice independent of spontaneous bacterial infection.

Breanne Y Farris Kelly L MonaghanWen ZhengCourtney D AmendHeng HuAmanda G AmmerJames E CoadXuefang RenEdwin C K Wan

Published in: Immunity, inflammation and disease (2019)

This is the first report to demonstrate a significant reduction of lymphocytes and multiple proinflammatory chemokines in the lungs following ischemic stroke in mice. These findings suggest that ischemic stroke directly impacts pulmonary immunity.

Keyphrases

atrial fibrillation
high fat diet induced
pulmonary hypertension
peripheral blood
insulin resistance
adipose tissue
metabolic syndrome
skeletal muscle