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Is prostatic adenocarcinoma with cribriform architecture more difficult to detect on prostate MRI?

Mason J BelueZoë BlakeEnis Cagatay YilmazYue LinStephanie A HarmonDaniel R NemirovskyJacob J EndersAlexander P KenigsbergNeil MendhirattaMichael RothbergAntoun ToubajiMaria J MerinoSandeep GurramBradford J WoodPeter C BlackIsmail Baris TurkbeyPeter A Pinto
Published in: The Prostate (2023)
The extent of disease for CBFM-containing tumors is difficult to capture on mpMRI. When comparing MRI lesions of similar dimensions and PIRADS scores, CBFM-containing tumors appear to have larger cancer yield on biopsy. Proper staging and planning of therapeutic interventions is reliant on accurate mpMRI estimation. Special considerations should be taken for patients with CBFM pattern on prostate biopsy.
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