Combined Hypophysitis and Type 1 Diabetes Mellitus Related to Immune Checkpoint Inhibitors.
Yasunori FujitaFumika KamitaniMasaaki YamamotoHidenori FukuokaYushi HirotaNobuharu NishiyamaNaho GodaYuko OkadaYuiko InabaHiroki NakajimaYukako KurematsuKeitaro KanieHiroki ShichiShin UraiMasaki SuzukiNaoki YamamotoHironori BandoGenzo IguchiHirotaka SutoYohei FunakoshiNaomi KiyotaYutaka TakahashiWataru OgawaPublished in: Journal of the Endocrine Society (2023)
We presented 3 cases of patients with combined endocrinopathies of hypophysitis and T1DM that may have been caused by anti-PD-1 antibodies. There was no difference in the time from ICI initiation to the onset of endocrinopathies between combined and single endocrinopathies. Further case accumulation and pathogenic investigations are required.