SS18-SSX drives CREB activation in synovial sarcoma.
Magdalene CyraMiriam SchulteRuth BertholdLorena HeinstEsther-Pia JansenInga GrünewaldSandra ElgesOlle LarssonChristoph SchliemannKonrad SteinestelSusanne HafnerThomas SimmetEva WardelmannSareetha KailayangiriClaudia RossigIlka IsfortMarcel TrautmannWolfgang HartmannPublished in: Cellular oncology (Dordrecht) (2022)
In conclusion, our data underline an essential role of CREB in SySa tumorigenesis and provides evidence for molecular targeted therapies.