Female reproductive function after treatment of childhood acute lymphoblastic leukemia.
Roxanne RoshandelMarloes van DijkAnnelies OverbeekGertjan J L KaspersCornelis Nils LambalkCatharina C M BeerendonkDorine BrestersMargriet Van der Heiden-van der LooMarry van den Heuvel-EibrinkLeontien C M KremerJacqueline J LoonenHelena J H Van der PalCecile M RonckersWim J E TissingBirgitta A B VersluysFlora E van LeeuwenMarleen H van den BergEline Van Dulmen-den Broedernull nullPublished in: Pediatric blood & cancer (2021)
Reproductive function of ALL survivors treated with CT only does not differ from controls. However, survivors additionally treated with RT seem to be at an increased risk of certain adverse reproductive outcomes. Providing personalized counseling about (future) reproductive health risks in this group is imperative.