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The Impact of Perilesional Heatsink Structures on Ablation Volumes in Laser Interstitial Thermal Therapy for Brain Metastases.

Shovan BhatiaChandler N BerkeCameron A RiveraNathaniel A CleriAnil MahavadiMartin A MerenzonAdham M KhalafallahAdam S LevyLekhaj C DaggubatiAlexis A MorellBrandon KayePier SanchezAshish H ShahRicardo J KomotarMichael E Ivan
Published in: Neurosurgery (2024)
This novel quantitative analysis shows that perilesional heatsinks contribute to asymmetric ablations. CSF spaces trended toward higher degrees of asymmetric ablations. Importantly, neurosurgeons may anticipate asymmetric ablations preoperatively if heatsinks are located within 13.3 mm of the laser probe midpoint. These preliminary results may guide surgical decision-making in LITT for metastatic brain lesions.
Keyphrases
  • brain metastases
  • small cell lung cancer
  • solid state
  • squamous cell carcinoma
  • high speed
  • high resolution
  • white matter
  • living cells
  • cerebral ischemia
  • multiple sclerosis
  • brain injury
  • mass spectrometry