The role of non-genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell death.

Takahiro KoyanagiYasushi SagaYoshifumi TakahashiKohei TamuraTakahiro YoshibaSuzuyo TakahashiAkiyo TaneichiYuji TakeiHiroaki MizukamiHiroyuki Fujiwara

Published in: Cancer reports (Hoboken, N.J.) (2023)

Progesterone and MPA exhibited a rapid cytocidal effect on PR-negative ovarian cancer cells through non-genomic action. Progesterone and MPA could be novel adjuvant therapies for ovarian cancer.

Keyphrases

cell death
estrogen receptor
copy number
early stage
gene expression
cell cycle arrest
pi k akt
sensitive detection