Serum biomarker-based early detection of pancreatic ductal adenocarcinomas with ensemble learning.

Nuno R NenéAlexander NeyTatiana NazarenkoOleg BlyussHarvey E JohnstonHarry J WhitwellEva SedlakAleksandra Gentry-MaharajSophia ApostolidouEithne CostelloWilliam GreenhalfIan JacobsUsha Menon J Justin Hsuan Stephen P PereiraAlexey ZaikinJohn F Timms

Published in: Communications medicine (2023)

The ensemble modelling strategy explored here outperforms considerably biomarker combinations cited in the literature. Further developments in the selection of classifiers balancing performance and heterogeneity should further enhance the predictive capacity of the method.

Keyphrases

convolutional neural network
systematic review
neural network
single cell
machine learning
squamous cell