CMV IgG is Associated with Physical Function but not Muscle Density in People with HIV.
Maheen Z AbidiTriin UmblejaEdgar T OvertonTricia BurdoJacqueline M FlynnMichael T LuJana TaronSamuel R SchnittmanKathleen V FitchMarkella V ZanniCarl J FichtenbaumCarlos MalvestuttoJudith A AbergEvelynne S FuldaAllison Ross EckardJennifer Manne-GoehlerJessica J TuanHeather J RibaudoPamela S DouglasSteven K GrinspoonTodd T BrownKristine M ErlandsonPublished in: Journal of acquired immune deficiency syndromes (1999) (2024)
Higher CMV IgG titer was associated with poorer physical function, not explained by prior immune comprise, inflammation, or muscle density or area. Further mechanistic studies are needed to understand this association and whether CMV-specific therapy can impact physical function in PWH.