Myostatin serum concentration as an indicator for deviated muscle metabolism in severe burn injuries.

Christoph WallnerJ M WagnerS DittfeldM DryschM LehnhardtB Behr

Published in: Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society (2018)

With regard to the muscle metabolism after thermal trauma, our data suggest an acute anabolic response, presumably to spare muscle mass, which is converted to catabolic conditions accompanied by muscle strength reduction in the chronic phase. Myostatin plays a crucial role in this orchestration and initial myostatin concentration may predict the long-term muscle strength.

Keyphrases

skeletal muscle
drug induced
liver failure
respiratory failure
early onset
electronic health record
big data
trauma patients
data analysis
deep learning