Impact of opioid analgesics on survival in cancer patients receiving immune checkpoint inhibitors.

Gozde KavgaciDeniz Can GuvenYunus KaygusuzEce KaracaOmer DizdarSaadettin KilickapSercan AksoyMustafa ErmanSuayib Yalcin

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2024)

Our study demonstrates an association between the concurrent use of OAs and reduced OS and PFS in patients treated with ICIs. While OA treatment serves as a surrogate marker for higher disease burden, it may also suggest a potential biological relationship between opioids and immunotherapy efficacy.

Keyphrases

chronic pain
pain management
papillary thyroid
squamous cell
locally advanced
risk assessment
combination therapy
childhood cancer