Fibroblast-growth-factor-23 in heart failure with preserved ejection fraction: relation to exercise capacity and outcomes.

Prathap KanagalaJayanth R ArnoldJamal N KhanAnvesha SinghGaurav S GulsinMohamed EltayebPankaj GuptaIain B SquireGerry P McCannLeong L Ng

Published in: ESC heart failure (2020)

Plasma FGF23 is higher in HFpEF compared with age-matched and sex-matched controls and is strongly associated with exercise incapacity and prognosis. FGF23 correlates with plasma markers of inflammation and renal impairment.

Keyphrases

high intensity
physical activity
oxidative stress
resistance training
body composition
metabolic syndrome