Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.

Shuwen Chen Yanbin Wang Liming Liao Li Meng Juanjuan Li Cheng Shi Hong Jing Han Xiaofeng Zheng Huan Shen

Published in: Stem cells international (2020)

The results indicated that BMSCs, HPMSCs, and their exosomes all exerted a certain repair effect on SVOG cells damaged by PM, and consistent repair effect was observed between exosomes and MSCs. The repair effect of exosomes secreted from BMSCs and HPMSCs on the SVOG cells was studied for the first time, and the results fully demonstrated that exosomes are the key carriers for MSCs to play their role.

Keyphrases

mesenchymal stem cells
induced apoptosis
stem cells
cell cycle arrest
umbilical cord
type diabetes
particulate matter
metabolic syndrome
insulin resistance
risk assessment