Mechanism Study of Cinnamomi Ramulus and Paris polyphylla Sm. Drug Pair in the Treatment of Adenomyosis by Network Pharmacology and Experimental Validation.

Keke Zhang Zhou Zhou Chuchu WangMengdie YuYiran Zhang Yaxin Shi Xin Wang Yang Liu Li Xu Wei Shi Zhiyong Liu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

We propose that the pharmacological mechanism of the C-P drug pair in the treatment of AM is related to inhibition of the PI3K/Akt pathway and promotion of apoptosis in AM ectopic lesions.

Keyphrases

oxidative stress
endoplasmic reticulum stress
drug induced
replacement therapy
adverse drug
cell cycle arrest
electronic health record