Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria.

Immaculada DoñaRaquel Jurado-EscobarJames R PerkinsPedro AyusoMaría Carmen Plaza-SerónNatalia Pérez-SánchezPaloma CampoGador Bogas-HerreraJoan BartraTorres María JoséMarek SanakJosé Antonio Cornejo-Garcia

Published in: Allergy (2019)

We present for the first time data regarding the role of COX-1 inhibition in NIUA. Patients with this entity show a similar pattern eicosanoid levels following ASA challenge to those with NECD. Further studies will help ascertain the cell populations involved and the underlying molecular mechanisms.

Keyphrases

drug induced
liver injury
anti inflammatory
single cell
electronic health record
cell therapy
adverse drug
big data
stem cells
deep learning
artificial intelligence