HIV-1 Nef-induced lncRNA AK006025 regulates CXCL9/10/11 cluster gene expression in astrocytes through interaction with CBP/P300.
Feng ZhouXiaomei LiuDongjiao ZuoMin XueLin GaoYing YangJing WangLiping NiuQianwen CaoXiangyang LiHui HuaBo ZhangMinmin HuDianshuai GaoKuiyang ZhengYoshihiro IzumiyaRen-Xian TangPublished in: Journal of neuroinflammation (2018)
Our findings uncovered the expression profiles of lncRNAs and mRNAs in vitro, which might help to understand the pathways that regulate astrocyte activation during the process of HAND.
Keyphrases
- gene expression
- antiretroviral therapy
- hiv positive
- hiv infected
- human immunodeficiency virus
- high glucose
- dna methylation
- hiv testing
- diabetic rats
- hepatitis c virus
- hiv aids
- genome wide analysis
- long non coding rna
- men who have sex with men
- drug induced
- network analysis
- south africa
- transcription factor
- stress induced